i wanted to provide an update on this topic. i decided to stop using Nexgard and go back to more natural methods, luckily these days there are natural oil infused collars available too.
Several weeks ago very shortly after giving the monthly dose, Miksa started getting into and excessive drinking and urination spiral, waking up in the middle of the night (he has not done anything like that since 11 weeks old..), going out for long (like 2 minutes without ever putting down his leg) pees, behaving very excited afterwards, in the middle of the night and then crashing from tiredness. It was always followed by flaky skin too. Bende some flaky skin as well. No other symptoms, but i still took Miksa to the vet, urine and blood analysis, everything came back perfect, no sign of infection or kidney issues, except the gravity of his urine was very low, due to the excessive drinking kind of washing out his system, so vet had no answer what could be the cause.
It took me some time to put together, that even in the past, if i have seem any abnormality, it was after administering Nexgard. We are in week 3 now, the toxin level in their bodies much lower, and i see less and less symptoms. So hopefully weaning them and going back to the natural method will work.
Obviously i will need to be much more vigilant, as tick season is starting it`s peak here....